Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | HDR is not inhibited by cysteine alkylating reagents at concentrations up to 2 mM | Methanosarcina barkeri | |
additional information | HDR is not inhibited by cysteine alkylating reagents at concentrations up to 2 mM | Methanosarcina thermophila | |
additional information | HDR is not inhibited by cysteine alkylating reagents at concentrations up to 2 mM | Methanothermobacter marburgensis |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Iron | coenzyme M binds to a [4Fe-4S] cluster in the active site | Methanosarcina barkeri | |
Iron | coenzyme M binds to a [4Fe-4S] cluster in the active site | Methanosarcina thermophila | |
Iron | coenzyme M binds to a [4Fe-4S] cluster in the active site | Methanothermobacter marburgensis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Methanosarcina barkeri | - |
- |
- |
Methanosarcina thermophila | - |
- |
- |
Methanothermobacter marburgensis | - |
formerly Methanobacterium thermoautotrophicum strain Marburg | - |
Purification (Comment) | Organism |
---|---|
- |
Methanosarcina barkeri |
- |
Methanosarcina thermophila |
- |
Methanothermobacter marburgensis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
coenzyme B + coenzyme M + methanophenazine | - |
Methanosarcina barkeri | N-(7-[(2-sulfoethyl)dithio]heptanoyl)-3-O-phospho-L-threonine + dihydromethanophenazine | - |
? | |
coenzyme B + coenzyme M + methanophenazine | - |
Methanosarcina thermophila | N-(7-[(2-sulfoethyl)dithio]heptanoyl)-3-O-phospho-L-threonine + dihydromethanophenazine | - |
? | |
coenzyme B + coenzyme M + methanophenazine | - |
Methanothermobacter marburgensis | N-(7-[(2-sulfoethyl)dithio]heptanoyl)-3-O-phospho-L-threonine + dihydromethanophenazine | - |
? | |
CoM-S-S-CoB + ? | - |
Methanosarcina barkeri | CoM-SH + CoB-SH + ? | - |
? | |
CoM-S-S-CoB + ? | - |
Methanosarcina thermophila | CoM-SH + CoB-SH + ? | - |
? | |
CoM-S-S-CoB + ? | - |
Methanothermobacter marburgensis | CoM-SH + CoB-SH + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
HDR | - |
Methanosarcina barkeri |
HDR | - |
Methanosarcina thermophila |
HDR | - |
Methanothermobacter marburgensis |
HdrB | catalytic subunit of HDR | Methanothermobacter marburgensis |
HdrC | catalytic subunit of HDR | Methanothermobacter marburgensis |
HdrD | catalytic subunit of HDR | Methanosarcina barkeri |
heterodisulfide reductase | - |
Methanosarcina barkeri |
heterodisulfide reductase | - |
Methanosarcina thermophila |
heterodisulfide reductase | - |
Methanothermobacter marburgensis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Methanosarcina barkeri | |
FAD | - |
Methanosarcina thermophila | |
FAD | - |
Methanothermobacter marburgensis |